The research

We tested the thesis. The market runs on outdated information.

Before building TrialBridge around Brazil's 2024 reform, we asked the people who actually pick trial countries whether the perception gap is real — and whether closing it changes their decision. It is, and it does.

Prolific + Tally · two waves N=125 unique complete 71 industry-qualified Fieldwork July 10–11, 2026 Directional, not powered
Three claims, three verdicts

The thesis, tested claim by claim

Each claim behind TrialBridge was written down before fieldwork. Here is how each one fared against the data.

Claim 1 — nobody knows the law changed
74%
had never heard of Lei 14.874/2024

The reform replaced the double ethics review with a single ~30-business-day review and capped ANVISA at 90 business days. Only 6% knew the details.

SupportedQ9 · n=125
Claim 2 — information alone moves intent
+0.95
intent shift after one paragraph about the reform

Likelihood to include Brazil in the next 12 months rose from 3.18 to 4.13 (0–10 scale). Among industry-qualified respondents: +1.11, with high intent going 23% → 37%.

SupportedQ8→Q10 · paired t=6.30 · p<.001
Claim 3 — the #1 barrier is what the law fixed
34%
cite regulatory approval timelines — the top barrier

41% among the industry-qualified, and the #1 single dealbreaker (20%). Add ethics review and start-up time: 34% of dealbreakers are things Lei 14.874 directly addressed.

SupportedQ2, Q3 · n=125
The natural experiment

One paragraph about the reform, read mid-survey

Respondents rated their likelihood to include Brazil (Q8), then read a one-line description of Lei 14.874, then rated again (Q10). Same person, same sitting — the only thing that changed was what they knew.

Intent to include Brazil in the next 12 months

0–10 scale · n=125
Beforeunaware baseline x̄ 3.18
Afterone paragraph later x̄ 4.13
Low intent (0–3) Mid (4–6) High (7–10) median 3 → 5
48% / 46% / 6%raised / held / lowered their score — 8 people went down, 60 went up
3.52 → 4.63industry-qualified only (n=71): +1.11, 56% raised, high intent 23% → 37%
+1.42 vs +0.59lift with prior LatAm exposure vs never-considered — familiarity compounds

Brazil after the paragraph (x̄ 4.13) outscores the rest of LatAm (Q11, x̄ 3.86) — the reform is a Brazil-specific advantage, not a regional halo.

What keeps Brazil off the list

Barriers, ranked — and who already fixed which

"Pick up to 3 biggest barriers to running a trial in Brazil / LatAm." Green tags mark the ones Lei 14.874 already addressed; the rest is what TrialBridge and its network cover.

  • Regulatory approval timelines Reform fixed this
    34% · 41% qualified
  • Site quality & consistency We built this
    26% · 32% qualified
  • Language / documentation
    26% · 25% qualified
  • No local relationships or familiarity We built this
    26% · 27% qualified
  • Importation / customs In our network
    24% · 31% qualified
  • Political / economic / currency risk
    22% · 27% qualified
  • Overall start-up time Reform fixed this
    18% · 23% qualified
  • Ethics committee review Reform fixed this
    16% · 18% qualified
  • Data quality & monitoring
    15% · 17% qualified

Multi-select, so columns don't sum to 100%. "Qualified" = pharma, biotech, CRO, and clinical-research-adjacent respondents (n=71). Asked one level deeper — "which ONE kills the decision?" — regulatory timelines leads again (20%), with "no local relationships" second (15%).

What would change their mind

They asked for de-risking, not discounts

"What would most increase the trials you'd place in Brazil / LatAm?" The top three asks map one-to-one onto what TrialBridge ships.

  • Local regulatory / feasibility experts In our network
    38% · 48% qualified
  • Vetted, quality-certified site network We built this
    34% · 41% qualified
  • Proof: recent fast start-up case studies
    28% · 34% qualified
  • SLA-backed start-up timeline guarantees
    25% · 31% qualified
  • Importation & customs support In our network
    24% · 21% qualified
  • Pre-identified investigators with patients We built this
    22% · 28% qualified
  • Contracting & budget templates
    19% · 23% qualified
  • Transparent site-cost benchmarks
    18% · 14% qualified

Pick up to 3 · N=125 · bars scaled to the top answer. Price levers (cost benchmarks) rank below trust levers (local experts, vetted sites, proof) — the objection is risk, not budget.

The competition

Brazil doesn't lose to Mexico. It loses to inertia.

"When Brazil competes for a trial slot, which country does it usually lose to?" — asked in wave 2. The answer isn't a rival market.

Where the slot goes instead

Pick up to 2 · wave 2, n=75
  • US — trial kept domestic
    48%
  • "We don't consider Brazil"
    21%
  • Mexico
    17%
  • Argentina
    13%
  • Spain
    12%
  • Australia
    9%
Brazil vs. its main alternative
81%
say Brazil is the same, worse — or they simply don't know

Don't know 33% · about the same 27% · somewhat/clearly worse 21%. Only 18% rate Brazil better. Nobody has shown them the difference — which is exactly why one paragraph moves intent.

Q13 · wave 2, n=75
When the decision happens

The country list locks before anyone calls a CRO

60%
lock the country list at concept or feasibility

Concept 30% + feasibility 30%. Only 6% wait for CRO selection — visibility has to arrive before the shortlist exists.

82%
have never executed a trial in Latin America

56% never considered it, 26% considered but didn't. Just 10% have touched Brazil — greenfield, not a knife-fight.

58%
opted into a follow-up interview

72 of 125 said yes to a 15-minute follow-up via Prolific — a warm panel for the next research round.

Sample & method

Who answered, and what we won't claim

DimensionBreakdown
RecruitmentProlific panel → Tally instrument (tally.so/r/9qyNOV), two waves
CompletesN=125 unique (wave 1 n=50 + wave 2 n=77, 2 duplicate IDs removed) · July 10–11, 2026
RolePharma 21% · clinical-research-adjacent 18% · biotech 11% · CRO 7% · other 43%
Qualified subsetn=71 (57%) — pharma, biotech, CRO, clinical-adjacent
Company HQUS 73% · UK/EU 21% · other 6% · Brazil 1%
Wave 2 additionsCompetitive questions: who Brazil loses to, Brazil vs alternative

Honest limits

  • Directional, not powered. N=125 from a single panel; treat point estimates as signals, not measurements.
  • Within-subject design. Before/after in one sitting can invite demand effects — though 46% held their score and 6% moved down, which argues against pure politeness.
  • Stated intent ≠ placed trials. We measured willingness, not behavior.
  • 43% adjacent respondents. "Other" roles are kept in the headline numbers and split out in the qualified cut throughout. Wave 2 skews US (combined HQ 73% US).

Full instrument, response data, and analysis available on request.

The gap is real. We built the bridge.

Decision-makers move the moment they can see what Brazil actually offers. TrialBridge puts that proof where the decision happens — at feasibility.